🩺 Melatonin Doesn’t Cause Heart Failure — But Your Use Still Might Be an Issue
Long-term melatonin use has recently been linked to a higher risk of heart failure, but that doesn’t mean melatonin causes heart problems. The claim stems from a preliminary study presented at the American Heart Association, where researchers reviewed five years of health records for adults with chronic insomnia. They found that 4.6% of long-term melatonin users were diagnosed with heart failure compared to 2.7% of non-users — the basis for the “90% higher risk” headline.
However, deeper analysis reveals that melatonin users were also more likely to be hospitalized for heart failure and nearly twice as likely to die of any cause. Those numbers don’t point to a supplement problem — they point to a population problem. People who rely on melatonin nightly often struggle with underlying insomnia, depression, or anxiety, all of which can increase cardiovascular risk.
The takeaway: melatonin isn’t the villain here, but it’s not the hero either. It’s best used for short-term sleep rhythm adjustments, like jet lag or shift changes. A 2022 review of 24 randomized trials found that melatonin didn’t significantly improve sleep quality, duration, or onset time. Neither the American Academy of Sleep Medicine nor the American College of Physicians recommends it for chronic insomnia.
If you’ve been taking melatonin nightly for a year or more, don’t panic about your heart — but do take it as a sign to address the root causes of your sleep issues. Better sleep hygiene, stress management, and professional guidance will do far more for your health than any over-the-counter pill.
Disclaimer: I am not a doctor, medical professional, or licensed health provider. The information shared here is for educational and discussion purposes only and should not be taken as medical advice. Always consult a qualified healthcare professional before making decisions about your health, supplements, or treatment options.






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